Serumcholinesterase als Modell eines Glykoproteins

Abstract

Human serum cholinesterase (EC 3.1.1.8) is a carbohydrate-rich glycoprotein, which reacts with 18 different lectins from plants and invertebrates by a specific precipitin reaction; most of the lectins combine with alkali-stable bound carbohydrate chains. One third of these lectin receptors appear after neuraminidase-treatment, two thirds can be demonstrated before and after removal of neuraminic acid. The specific lectin receptors of the alkali-labile carbohydrate chains are characterized and analyzed by chemical and serological methods.