Serum Uric Acid Level in Hypertensive Patients with Acute Myocardial Infarction

Abstract

ABSTRACT Objectives To estimate serum uric acid level in hypertensive patients with acute myocardial infarction and hypertensive patients without myocardial infarction. Study Design Cross-sectional study. Setting Department of Medicine, Mayo Hospital, Lahore. Duration of study with dates Study was carried over a period of six months from 01-01-2007 to 30-06-2007. Subjects and methods Eighty hypertensive patients were included in the study out of which 40 patients with acute myocardial infarction were put in MI group and 40 patients without any history of myocardial infarction were labeled as non-MI group. Results Mean age of the patients in MI group and non-MI was found to be 50.0±12.4 and 51.8±10.1 years, respectively. Results of Serum uric acid level in MI group were 6.9±1.0 mg/dl [0.407 ± 0.059 mmol/L ] and in non-MI group were 5.8±1.5 mg/dl [0.342 ± 0.088 mmol/L] (p<0.001). (where 1 mmol/L = 16.78 mg/dl or 1 mg/dl = 0.059 mmol/L). Conclusion The present study proved that raised serum uric acid level can cause hypertension and further rise can lead to MI. Key words Serum uric acid, Myocardial infarction, Hypertension