Abstract
Serum uric acid in smokers
Highlights
No significant differences in the age, serum creatinine, spot urine uric acid/urine creatinine ratio and fraction excretion of uric acid between two groups where as serum uric acid was significantly lower in smokers
Heavy, moderate and mild smokers showed no significant differences in the age, urine uric acid/urine creatinine ratio, fraction excretion of uric acid, serum creatinine and serum uric acid except a significant lower serum uric acid value in the heavy smoker compared with moderate and mild smokers
The significant low serum uric acid level in smokers is due to the reduction of endogenous production as a result of chronic exposure to cigarette smoke that is a significant source of oxidative stress and as this reduction is proportionate with the duration and number of cigarette smoked/day and as low uric acid predispose to cardiovascular diseases as proved by other studies, its recommended for smokers to stop or reduce smoking with the use of serum uric acid as a routine test for follow-up as it is inexpensive, simple to reflect antioxidant level
Summary
To demonstrate the possible effect of smoking on serum uric acid level. Methods: The study was conducted during the period from March to June ٢٠٠٨ in Mosul city as a case control study.
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