Abstract
Serum protein binding determination for erythromycin, lincomycin, and clindamycin utilizing ultrafiltration of serum containing antibiotic in a concentration of 5 mcg./ml. and tube dilution techniques revealed a high degree of binding: erythromycin base, 73%; erythromycin propionate, 93%; lincomycin, 72%; and clindamycin, 94%.
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