Abstract
Hemolytic activity for animals infected with various Babesia species is well reported. In this study, we confirmed that serum of Babesia rodhaini-infected mice also showed hemolytic activity. Erythrocytes from non-infected mice were lysed by co-incubation with B. rodhaini-infected serum. Catalase activity of the non-infected target erythrocytes was suppressed after this co-incubation with the hemolytic serum of B. rodhaini-infected mice. Furthermore, serum hemolytic activity was inhibited when target erythrocytes were incubated with hemolytic serum in the presence of exogenous catalase. Our study indicated that hemolytic serum can down-regulate the antioxidant capacity of non-infected healthy erythrocytes, possibly as a result of catalase activity, thereby leading to hemolysis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
