Abstract
In the present study serum Malondialdehyde (MDA) and Vitamin C profiles of conversion disorder patients were compared with control and evaluated the correlation between MDA and vitamin C level was evaluated with their socioeconomic factors. Conversion disorder patients (n=45), age ranging from 17 to 41 years, were randomly recruited from the Department of Psychiatry, Bangabandhu Sheikh Mujib Medical University Hospital, Dhaka, Bangladesh for this study. Control group also included 45 healthy individuals matched by the socio-demographic status to that of the patients. Blood samples were analyzed for determining MDA and vitamin C using Ultraviolet-Visible (UV-VIS) spectroscopy. Serum concentrations of MDA and vitamin C of conversion disorder patients were 2.19 ± 1.47 and 19.23 ± 5.59 μmol/L respectively while these were 2.11 ± 0.88 and 21.00 ±4.96 μmol/L in control subjects respectively. Socioeconomic data revealed that most of the patients were young female and unmarried. The mean BMI of patients (21.05 ± 3.39) were not significantly different (P > 0.05) from the control subjects (20.86 ± 1.86). Moreover, statistical analysis revealed that there were no significant correlation between MDA, vitamin C concentrations and socioeconomic factors. The results of our study have shown higher oxygen free radical production, evidenced by increased levels of MDA and decreased levels of ascorbic acid which supports the oxidative stress in conversion disorder patients. DOI: http://dx.doi.org/10.3329/dujps.v10i1.10017 DUJPS 2011; 10(1): 59-64
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Dhaka University Journal of Pharmaceutical Sciences
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.