Abstract
used as an indicator of oxidative stress in cells and tissues. Lipid peroxides, derived from polyunsaturated fatty acids, are unstable and decompose to form a complex series of compounds. These include reactive carbonyl compounds, of which malondialdehyde (MDA) is the most abundant. Therefore, measurement of malondialdehyde is widely used as an indicator of lipid peroxidation. Increased levels of lipid peroxidation products have been associated with a variety of chronic diseases in both humans and model systems. 8-10 For example, HIV infection is associated with oxidative stress, as has been demonstrated in adult, seropositive individuals. One study showed that serum malondialdehyde (MDA) concentration in HIVinfected children was significantly higher than in control children. 6,7 The aim of this study was to investigate the difference in the serum malondialdehyde levels (an end-product of lipid peroxidation) between normal and T. gondii-infected individuals (IgG seropositive but no symptoms).
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