Abstract
Serum magnesium determinations were obtained on 10 dogs and 11 patients undergoing fractionated irradiation to the pelvis and lower abdomen. Five of dogs received oral prednisone during irradiation. There was no significant change in magnesium concentration in either the control dogs or the patients, but there was a significant increase in stool frequency in both the dogs and patients. A significant increase in magnesium concentration was noted in the dogs receiving prednisone. It is concluded that radiation-induced diarrhea is not caused by reduced serum magnesium concentration.
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