Serum Liver Enzyme Levels: A Hospital-Based Observational Study from Kashmir

Abstract

Background: Liver disorders are one of the most common causes of health problems all over the world owing to evolving lifestyles and dietary patterns. In this retrospective study, we aimed to explore the impact of dietary habits on liver enzymes among the Kashmiri population. Methods: A total of 18462 patients were registered in the outpatient/Inpatient sections of the tertiary care hospital of Kashmir for various investigations from March to November 2020. In the liver function profile, a total of 7715 samples were tested for Aspartate transaminase (AST), 12084 for Alanine transaminase (ALT), 12573 for total bilirubin, 131472 for albumin, Alkaline phosphatase for 12762, and 12181 for Lactate dehydrogenase (LDH) parameters. Results: The average value documented for aspartate transaminase (AST), alanine transaminase (ALT), total bilirubin, total protein, and albumin were 39.06 U/L, 38.81U/L, 0.91mg/dL, 7.31g/dL, and 4.22g/dL respectively which are considered normal. However, ALP and LDH were found to be little elevated among various liver function parameters. Alkaline phosphatase (ALP) and Lactate dehydrogenase (LDH) had average values of 148.66 and 260.25U/L, respectively. Conclusion: Our findings revealed the rising levels of alkaline phosphatase (ALP) and Lactate dehydrogenase (LDH), this paradigm shift could be attributed to a sedentary lifestyle and unique dietary habits.