Serum lipids, serum uric acid and glucose tolerance in coronary heart disease.

Abstract

ABSTRACTIn 100 patients (mean age, 51) with angina pectoris due to coronary heart disease (documented), determinations were made of the serum cholesterol, triglyceride and uric acid levels on two separate days at least two weeks apart; also (in the absence of fasting hyperglycemia) glucose tolerance tests were performed after oral administration of 100 gm of glucose. In 95 per cent of the 100 patients, the serum cholesterol level was above 200 mg/100 ml. In 51 per cent there was hypertriglyceridemia. In no patient was there hypertriglyceridemia in association with a serum cholesterol level below 200 mg/100 ml. Thirty‐five per cent of the 100 patients showed abnormal glucose tolerance. Eleven per cent of the 100 patients had hyperuricemia. An elevated concentration of serum cholesterol was the most common metabolic abnormality associated with angina pectoris due to coronary artery disease.