Abstract
BackgroundLittle is known about serum lipid levels comparison of patients with acute myocardial infarction (AMI) in Hakka patients in southern China. To estimate the prevalence lipid profiles in Hakka patients with AMI in southern China.MethodWe analyzed 1382 patients with a first AMI in Hakka patients in southern China between Jan. 2015 and Dec. 2015.ResultsOur findings demonstrated that low-density lipoprotein cholesterol (LDL), total cholesterol (TC), and triglyceride (TG) were higher in nonelderly than in elderly for males. There were significant differences in TC, LDL, HDL, and TG among various age groups for both males and female patients (P < .05). TC, LDL, HDL, and TG were higher in females than males for the elderly, and the LDL levels of females were higher in 70–79,80–89 year age groups than males. The HDL level of female patients was higher than males in those 50–59, 60–69, and 70–79 year age groups. Compared with males, females had higher level of TG in the 60–69, 70–79, and 80–89 year age groups and had higher level of TC in the 50–59, 70–79, and 80–89 year age groups, respectively. Isolated high TG (normal LDL + normal HDL+ high TG) was most common type of combined dyslipidemia for female elderly (22.2%), female nonelderly (23.2%) and male elderly (24.1%) patients.ConclusionOur results confirmed that serum lipid levels varied in age and gender in Hakka patients with acute myocardial infarction. Dyslipidemia is more prevalent in the non-elderly than in the elderly for males. Levels of TC, LDL, HDL, and TG were higher in females than males for the elderly Hakka population in southern China.
Highlights
Little is known about serum lipid levels comparison of patients with acute myocardial infarction (AMI) in Hakka patients in southern China
Some clinical studies show that the incidence of coronary artery disease (CAD) continue to increase; about 1 in 5 Chinese is suffering from CAD [2].Cardiovascular disease is regarded as a multifactorial disease, which affected by the environment and genetic factors
A growing evidences indicates that elevated concentrations of TG, total cholesterol (TC), low-density lipoprotein cholesterol (LDL)-C and decreased High-density lipoprotein cholesterol (HDL)-C accelerate the development of atherosclerotic plaques [4,5,6,7]
Summary
Little is known about serum lipid levels comparison of patients with acute myocardial infarction (AMI) in Hakka patients in southern China. Previous studies have shown age- and gender- differences in lipid profile in AMI patients in East China, and dyslipidemia is biased toward young people, at the same time, some researchers reported the lipid metabolism in urban and rural areas of southern China [8].little is known about age and gender-related lipid levels comparison of patients with acute myocardial infarction (AMI) in the Hakka population of southern China. Understanding age-and gender-related differences in post-AMI lipid profiles and the characteristic of dyslipidemia in the Hakka population in southern China may provide important implications for treatment and guide strategy to reduce age- and gender-related differences in outcomes
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