Abstract
Serum lipid peroxide level and vitamin B2 status of 90 pregnant (27 in the 1st trimester, 23 in the 2nd trimester, and 40 in the 3rd trimester) and 33 healthy non-pregnant women were examined.Serum lipid peroxide level of the pregnant women increased as pregnancy progressed, and the level at the 3rd trimester was significantly higher than that of the non-pregnant women. Thirty pregnant women had an increase in serum lipid peroxide level and 10 of them had marginal riboflavin deficiency as judged by their erythrocyte glutathione reductase (EGR) activity coefficients. The number of pregnant women having both increased serum lipid peroxide level and marginal riboflavin deficiency increased with the advancement of pregnancy (0 in the 1st trimester, 1 in the 2nd trimester, and 9 in the 3rd trimester). A weak positive correlation between serum lipid peroxide level and EGR activity coefficient of the pregnant women was found in the 3rd trimester. These results indicate that the increase in serum lipid peroxide level during pregnancy, particularly at the late stage, may be at least partly attributable to marginal riboflavin deficiency.
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