Abstract
The effect of luteinizing hormone-releasing hormone/follicle stimulating hormone (LH-RH/RSH-RH) on serum luteinizing hormone (LH) concentrations was studied in Angus heifers and cows. The animals received 150 mcg LH-RH/FSH-RH in acidified saline intravenously via an indwelling catheter every 4 hours for 96 hours on Days 16 through 19 of the estrous cycle. Mean serum LH vaues were significantly higher in treated heifers compared with controls (p <.01). During the 1st half of the treatment period peak serum LH values were significantly higher than those observed during the 2nd half (p <.01). LH values returned to near basal concentrations within 4 hours of treatment. Cows ovariectomized at the end of the treatment period did not show any marked differences in follicular fluid volume or corpora lutea weight compred with controls. The results indicate that the regimen failed to stimulate ovarian activity in the cow though the decline and subequent rise in peak serum LH during treatment is not yet understood.
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