Abstract
Background A variety of liver diseases accompany significant elevation of both type IV collagen 7S (IV-c-7S) and procollagen type III N-terminal proppeptide (P-III-P), suggesting the presence of liver fibrosis. We investigated whether metastatic liver tumors from colorectal carcinoma cause hepatic fibrosis at metastatic sites, and if serum levels of collagen precursors would suggest fibrous changes of metastatic liver tumors.
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