Abstract
The study was undertaken to determine the correlation of serum LDH in pre eclampsia and eclampsia and perinatal outcome. This is a hospital based comparative case control study done in Department of Obstetrics & Gynaecology SMS Medical College, Jaipur between March 2014 to Oct 2015 on 140 subjects including normotensive , mild pre eclamptic , severe pre eclamptic and eclamptic pregnant women after 28 weeks of gestation before termination of pregnancy. Serum LDH levels were recorded and perinatal outcomes observed. The mean value of serum LDH in control group was 391.4 ± 10.9 IU/L, in mild pre eclampsia 531.5 ± 24.5 IU/L, in severe preeclampsia 922.1± 515.5 IU/L and in eclampsia 1497.6 ± 602.1 IU/L. The difference in serum LDH level was highly significant (P<0.001).Higher LDH levels were associated with High Blood Pressure and had significant correlation with poor perinatal outcome. Thus we conclude that High serum LDH levels correlate well with poor maternal and perinatal outcomes in patients of Preeclampsia and Eclampsia.
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