Abstract
Serum insulin and blood sugar were investigated in ten normal-weight diabetics with maturity-onset diabetes and in 12 controls before and after intravenous injection of 25 gm d-glucose without and during simultaneous infusion of isoprenaline 2 µg/min. A significant increase in serum insulin concentration was found after isoprenaline in both groups, both before and after injection of glucose. The increase in serum insulin level in the diabetics after isoprenaline was found to be normal, although the increase in insulin concentration following glucose was greatly reduced. It is concluded that in patients with maturity-onset diabetes there is presumably a defect of the glucose turnover in the B cells, whereas the process of insulin secretion itself is normal.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
