Abstract
SummarySerial estimations of serum heat stable alkaline phosphatase (HSAP) were performed in 28 normal healthy primigravidae at 16, 20, 25, 30, 34 and 38 weeks gestation, during labour and in the puerperium. Serum HSAP was measured on a further 15 normal primigravidae at 30, 34 and 38 weeks. Urinary pregnanediol output was measured at 20, 25, and 30 weeks and urinary oestriol estimations made at 30, 34 and 38 weeks.There was a progressive increase in the level of serum HSAP with advancfing pregnancy, the peak being reached during the second stage of labour followed by a gradual fall ink the puerperium. There was no correlation between serum HSAP level and urinary pregnanediol output, crude baby weight or placental weight. Significnat degrees of correlation were demonstrated between serum HSAP level and urinary oestriol output at 30, 34 and 38 weeks.
Published Version
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