Abstract
SummaryNew Zealand strain rabbits were given varying dosages of total body x-irradiation. SGOT determinations were made at various intervals in the post-irradiation period up to 168 hours following irradiation. Initially the blood specimens were drawn by direct cardiac puncture and the results in these instances were too variable to be used for diagnostic or prognostic purposes. When the free bleeding technic was used for obtaining blood specimens, more consistent results were obtained. Average SGOT values for pre- and one hour post-irradiation were of the same order of magnitude. An increase in GOT activity was observed as early as 5 hours after total body irradiation and remained elevated for 25 hours. After 49 hours post-irradiation SGOT levels returned to normal. There was no correlation between SGOT activity and total irradiation or survival time of the animal.
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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