Abstract
ABSTRACT Determinations were made of the serum glutamic-oxalacetic transaminase and serum glutamic-pyruvic transaminase levels in patients with toxemia of pregnancy and in pregnant women with symptoms of liver damage supposed to be secondary to the pregnant state. The transaminase value was found to be high in about 30 per cent of the former and in more than 50 per cent of the latter. The only demonstrable relationship between a high transaminase value and clinical symptoms or other laboratory findings was the correlation with signs of co-existing liver disorder or damage. The assumption that the increase in transaminase activity is due to hepatocelluar damage is also supported by the observation that the increase in the serum glutamic-oxalacetic transaminase value was usually accompanied by an increase in the serum glutamic-pyruvic transaminase value, and that in some cases only the latter was increased above the normal level.
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