Abstract

Background Histamine intolerance (HIT) is characterized by an imbalance between histamine intake and the capacity for histamine degradation. The main enzyme for metabolizing ingested histamine is diamine oxidase (DAO). Determining DAO activity in serum may be useful in diagnosing HIT.

Highlights

  • Histamine intolerance is mainly caused by an imbalance of histamine intake and the capacity for histamine metabolism and degradation

  • Determination of diamine oxidase (DAO) activity in serum might be useful for differential diagnosis of histamine intolerance

  • Serum DAO activity was measured with Enzyme immunoassay for the quantitative determination of histamine-degradation activity by DAO in serum

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Summary

Introduction

Histamine intolerance is mainly caused by an imbalance of histamine intake and the capacity for histamine metabolism and degradation. Serum diamine oxidase (DAO) activity as a diagnostic test for histamine intolerance Ema Music*, Mira Silar, Peter Korosec, Mitja Kosnik, Matija Rijavec From Food Allergy and Anaphylaxis Meeting 2011 Venice, Italy.

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