Serum Cardiac Troponin I, Creatine Kinase (CK), and CK-MB in Early Posttraumatic Rhabdomyolysis

Abstract

Early diagnosis of posttraumatic cardiac injury is important for patient outcome (1) but a concomitant rhabdomyolysis may impede its detection by biochemical means. Cardiac troponin I (cTnI) might be a useful tool to specifically assess myocardial damage in trauma patients. We report here serum cTnI, creatine kinase (CK), and CK isoenzyme MB measurements in multiple injured patients with rhabdomyolysis. Successive trauma patients with rhabdomyolysis [CK activity >500 U/L] during the first 24 h after admission were studied in accordance with the Helsinki Declaration. Exclusion criteria were age >55 years, Injury Severity Score (ISS (2)) <16, and history of prior cardiac or renal disease. Patients were considered to have chest trauma when the chest Abbreviated Injury Score (3) was ≥2. Electrocardiography and a transesophageal echocardiography (HP …