Abstract

Elevated serum bile acid levels are suggested to be a diagnostic tool as well as a predictor for mortality. After synthesis in the liver, and metabolization by intestinal microflora, bile acids are re-internalized. Characteristic liver damage, changes in microbiome and gut barrier dysfunction are likely to influence bile acid profilesaetiology-dependent. Therefore, we examined changes in bile acid profiles typical for different aetiologies of cirrhosis.

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