Abstract

There is scarce information about altered aspirin – esterase (AE) activities in various physiological and pathological states, as well as the putative agents modulating this activity. Since there are no data on AE levels in cord blood, we set up this study to measure its activity in neonates' cord blood and in adults, using an optimized technique developed in our laboratory. We performed a case-control study with 28 newborns, and control adult subjects were selected from a healthy population of hospital workers. Aspirin esterase activity in cord blood was 60 ± 12 nmol/mL/min vs 87 ± 12 nmol/mL/min in adults, p r = 0.86 p

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