Abstract

SYSTEMIC lupus erythematosus in man has been regarded as a classic autoimmune disorder1, and its clinical and pathological features have been associated with the occurrence of certain autoantibodies. A thymic abnormality in the disease was originally postulated by Burnet2, and was confirmed recently by Burnet and Mackay3. This finding established in systemic lupus erythematosus., like myasthenia gravis, the association between a clinical disorder, serum autoantibodies and a thymic change.

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