Abstract
Antibody levels of IgG, IgA and IgM reactive to the trypsin‐like enzyme of B. gingivalis were measured by enzyme‐linked immunosorbent assay in serum samples from control subjects with clinically healthy gingiva, patients with adult periodontitis (AP) and patients with rapidly progressive periodontitis (RPP). Both AP and RPP patients had significantly higher levels of specific IgG and IgA antibodies than control subjects with healthy gingiva (p<0.001 in both cases). No significant difference was observed between the specific IgM antibody activity in the AP group compared to the control group. However, a significant difference was seen (p<0.01) for IgM activity in the RPP group compared to controls. The results indicate that the trypsin‐like enzyme of B. gingivalis is produced in vivo in sufficient amounts to be immunogenic to the host and particularly in patients with AP or RPP.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.