Abstract

Trypanosoma brucei, Federe strain, caused an acute infection in rats after intraperitoneal inoculation of 106 trypanosomes. Parasitemia occurred from day 3 post-infection (pi) with peak parasitemia from day 7 pi. Anemia was observed between days 7 and 11 pi. The serum triglyceride concentration was comparable with the control value on day 7 pi, but increased (P 0.05) significantly during the infection. It was concluded that the decreased hepatic contents of these lipids were consistent with the serum lipid concentration, which did not seem to favor lipid uptake by hepatocytes.

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