Abstract
BackgroundAllergic rhinitis is the most prevalent allergic disease, and the prevalence and sensitization patterns differ among countries. Identifying the most common inhalant allergen in each region plays a key role in the diagnosis and management of allergic rhinitis. There are no data available about the most prevalent aeroallergen among allergic rhinitis patients in Egypt. The aim of this study is to evaluate the prevalence of positive serum allergen-specific IGE to common inhalant allergens among allergic rhinitis patients in Egypt. A cross-sectional study was conducted on 354 allergic rhinitis patients, serum allergen-specific IGE was measured by using the Immuno CAP system to 16 common regional aeroallergens including (pollens, mite, molds, animal dander, and cockroach).ResultsThe overall rate of sensitization to any allergen was 74.6%. Dermatophagoides pteronyssinus, birch pollens, and Dermatophagoides farina were the most prevalent allergens (29.7%, 23.7%, and 18.6%), respectively. Cladosporuim molds were the least prevalent individual allergens (1.7%).ConclusionOur data suggest that Dermatophagoides pteronyssinus and birch pollens were the predominant allergen sources among allergic rhinitis patient in Egypt.
Highlights
Allergic rhinitis is the most prevalent allergic disease, and the prevalence and sensitization patterns differ among countries
Allergic rhinitis (AR) is induced by a reaction mediated by immunoglobulin E in allergen sensitized patient and is characterized by recurrent sneezing, runny nose, nasal congestion, and itchy nose, which most often associated with ocular itching, redness, and/or lacrimation in 60– 70% of cases [1]
The prevalence of AR is very high in Egypt, no data are available on the most common aeroallergens, so this study aims to assess the prevalence of positive serumspecific IgE to various common aeroallergens among patients with allergic rhinitis in Egypt, to develop an effective strategy for the prevention and management of allergic rhinitis
Summary
Allergic rhinitis is the most prevalent allergic disease, and the prevalence and sensitization patterns differ among countries. Identifying the most common inhalant allergen in each region plays a key role in the diagnosis and management of allergic rhinitis. There are no data available about the most prevalent aeroallergen among allergic rhinitis patients in Egypt. The aim of this study is to evaluate the prevalence of positive serum allergen-specific IGE to common inhalant allergens among allergic rhinitis patients in Egypt. A cross-sectional study was conducted on 354 allergic rhinitis patients, serum allergen-specific IGE was measured by using the Immuno CAP system to 16 common regional aeroallergens including (pollens, mite, molds, animal dander, and cockroach). Allergen-specific IgE tests are very specific and sensitive. One of their benefits is that medication and skin lesions do not affect the results [5]
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