Abstract
Rat serum acid phosphatase activity was measured before hemorrhage, after one hour of hemorrhage and after two hours of hemorrhage. Rats were pretreated with either estradiol, corticosterone, prednisone or DMSO. Control groups were not pretreated and one of the control groups underwent the surgical procedures but was not hemorrhaged. Serum acid phosphatase activity increased in all groups hemorrhaged compared to those not hemorrhaged. DMSO pretreated rats showed a greater change of activity than did the hemorrhaged control group. Corticosterone or estradiol pretreatment significantly decreased activity due to shock. There was no significant difference between male and female tolerance to shock, but initial activity of estradiol pretreated males was similar to untreated females and significantly lower than untreated males.
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