Abstract
Only five cases of recurrence of malignant mixed Mullerian tumor (carcinosarcoma) from the ovarian carcinoma have been published in the literature to our knowledge. A 64-year-old woman first underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy because of pelvic mass. Histological diagnosis was serous papillary carcinoma of the left ovary. After six courses of chemotherapy, CA125 level returned to normal range. However, she had persistent multiple mediastinal and para-aortic lymphadenopathies in spite of additional six courses of chemotherapy. Then she underwent the second operation about 2 years after primary surgery. Multiple excisional biopsies were taken from subcutaneous tissue, over the bowels and the left external iliac artery. The histopathological diagnosis which was confirmed by immunohistochemical study was malignant mixed Mullerian tumor for all metastatic foci. A rare case of ovarian serous papillary carcinoma recurring as malignant mixed Mullerian tumor is reported.
Highlights
Carcinosarcomas known as malignant mixed Mullerian tumors are uncommon neoplasms of the female genital tract
We report a case of ovarian serous papillary carcinoma which recurred as carcinosarcoma which is homolog type in contrast to others in the literature
Carcinosarcomas known as malignant mixed Mullerian tumors are rare neoplasms of the female genital tract
Summary
Carcinosarcomas known as malignant mixed Mullerian tumors are uncommon neoplasms of the female genital tract. Five cases have been reported in the literature, to our knowledge [4,5,6,7] These tumors are biphasic with malignant epithelial and malignant mesenchymal components. In recent years, these tumors are thought to be metaplastic carcinomas. These tumors are thought to be metaplastic carcinomas These five cases and our case provide further evidence that carcinosarcoma is derived from carcinoma [4,5,6,7]. We report a case of ovarian serous papillary carcinoma which recurred as carcinosarcoma which is homolog type in contrast to others in the literature
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