Serotype distribution and drug resistance analysis of shigella in Henan province between 2001 and 2010

Abstract

Objective To investigate the serotype distribution and drug resistance situation of shigella in Henan province between 2001 and 2010 through the serotype,AST method and provide some reference to public health research and clinical treatment.Methods Two thousand three hundred and forty - seven strains of shigella isolated from diarrhea surveillance point in Henan province from 2001 to 2010 year were tested by morphological -biochemical identification,serotyping and AST test.Results Two thousand three hundred and forty - seven strains of shigella include four main groups by serotyping:S.flexneri( 1975strains:F2a35.09％,F4c26.73％,F1a16.96％ ),S.sonnei(369 trains),S.dysenteriae(2 strains)and S.boydii(1 strains).The AST test of 1008 shigella strains by K -B method showed a severe anti - drug conditions to 17 kinds of antibiotics,especially the number of multi - resistant strains were increasing rapidly in ten years.Conclusions The serotype distribution of strains are changing in the past ten years.AST test showed most bacterium have a high resistance and multi -resistance to antibiotics which used in shigella infection treatment,we should pay attention to this phenomena seriously and take actions for the clinical treatment and public health benefit. Key words: Shigella; Serotype; Drug - resistant rates; Multi - drug resistance