Abstract
The presence of serotonin (5-HT)-like immunoreactivity has been detected in ganglionar cell bodies of the nodose ganglia of the cat, using the peroxidase-antiperoxidase immunohistochemical method, applied to sections of ganglia previously embedded in paraffin. The antibodies were raised in rabbits following injection of 5-HT conjugated to bovine serum albumin, with formaldehyde as the condensation reagent. Immunoreactive cell bodies are morphologically and topographically described. The ubiquitous distribution and non-uniform labelling suggest that these 5-HT containing vagal neurones may give rise to several functionally different 5-HT types in vagal afferent fibres.
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