Abstract

Lithium hydroxybutyrate administered in the morning exhibits sedative effect, weakens memory consolidation, accelerates extinction of conditioned active avoidance reaction, and inhibits synthesis and catabolism of serotonin in the brain. When administrated in the evening, this drug apart from its sedative effect, improves learning and memory, prolongs memory retention, accelerates synthesis, and inhibits catabolism of serotonin.

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