Abstract
Serotonin syndrome is an iatrogenic drug‐induced synaptic serotonin concentration related toxidrome. A 29‐year‐old man developed agitation, tachycardia and myoclonus of limbs after an intramuscular injection of 100 mg tramadol. He had recently been given multiple medications, including dextromethorphan (DXM) by a private doctor for flu‐like symptoms. The patient was stabilised with diazepam, midazolam and supportive treatment. Both tramadol and DXM could cause the serotonin syndrome, but usually in combination with monoamine oxidase inhibitors or serotonin reuptake inhibitors. This was the first reported case in the English literature of serotonin syndrome with tramadol and DXM. Therefore, a detailed drug history and knowledge of potential serotonergic drugs are important.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
