Serotonin Syndrome in a Patient Using Paroxetine and Bupropion

Abstract

Serotonin syndrome is an important clinical condition that can occur after excessive central serotonergic activity, generally secondary to the use of combinations of antidepressants. Selective serotonin reuptake inhibitors and bupropion are frequently used in the treatment of major depression in clinical practice. Few cases of serotonin syndrome due to the use of serotonergic antidepressants and bupropion have been reported in the literature. The current case report presents a patient who underwent the serotonin syndrome after the administration of paroxetine and bupropion.