Abstract
Iontophoretically applied serotonin (5HT), substance P (SP), thyrotropin releasing hormone (TRH) and proctolin all enhanced spinal motoneuron activity evoked by glutamate in urethane-anesthetized rats. 5HT and SP produced more consistent facilitation of excitability both within and between motoneurons than did TRH and proctolin which failed to facilitate several motorneurons. It is concluded that 5TH, SP, TRH and proctolin, which appear to co-exist in various combinations in ventral horn terminals near spinal motoneurons, have complimentary effects on motoneuron excitability.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
