Abstract
The gene encoding for α-synuclein (SNCA) was the first to be linked to familial Parkinson's disease.1 At the same time, α-synuclein was identified as the main component of Lewy bodies, which are present in both familial and idiopathic Parkinson's disease.2 The Ala53Thr (A53T) SNCA mutation is associated with a similar clinical phenotype to the sporadic disease, albeit with earlier age-of-onset and faster disease progression.3,4
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have