Abstract
The study involved 286 individuals from different regions of Bosnia and Herzegovina, whose sera were tested in the Laboratory for specific diagnosis of human brucellosis in Microbiology Department of Medical Faculty of University in Sarajevo, during the period from 2000. to 2003. Sera were tested using Brucelloslide Test, qualitative agglutination test Rose Bengal. Using the agglutination test, we serologically confirmed a diagnosis of human brucellosis in 59 (20.62%) seropositive individuals, whereof 38 (64.40%) men and 21 (35.60%) women. Individuals with human brucellosis were the most present in the age group of 31-40 (22.03%) and 41-50 (22.03%). One serologically confirmed death case was registered. The most seropositive individuals were from Zenica-Doboj Canton (32.20%), Sarajevo Canton (28.82%), Herzegovina-Neretva Canton (23.73%), Central Bosnia Canton (13.55%) and Una-Sana Canton (1.70%). During our four-year study, it was serologically confirmed that human brucellosis is present in Bosnia and Herzegovina and, through seropositive testing, we revealed the level of general exposition to Brucella spp. on wider area of Bosnia and Herzegovina.
Highlights
Genus Brucella is consisted of small, immobile, Gramnegative coccobaccili which are pathogenic for humans and animals
Brucellosis is a zoonosis of the world-wide importance, especially in developing countries
Effective control steps in ranch industry, as well as more frequently consuming unpasterized milk products, lead to the fact that brucellosis is disease most commonly caused by nutrition ( )
Summary
Genus Brucella is consisted of small, immobile, Gramnegative coccobaccili which are pathogenic for humans and animals. Brucellae are intracellular parasites that can be transmitted to a range of animal species, including humans ( ). Four Brucella species, B. abortus, B. melitensis, B. suis and B. canis, can cause brucellosis when transmitted to humans. The treatment of brucellosis includes a logn-term antibiotic therapy, with recurrences if the therapy is discontinued too early or if microorganisms are in deep focus of infection. These recurrences usually occur in or months after the therapy discontinuation. Controlling and supervising brucellosis is based on limited disease spreading and possible eradication of the infection in animals, pasterizing the milk and milk products, and reducing professional risk, wherever it is possible
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