Serosurvey for assessing PPR vaccination status in rural system of Chhattisgarh state of India

Abstract

In this study, post vaccination seroconversion to Peste des petits ruminants (PPR) virus in small ruminants was assessed since annual mass vaccination campaign (MVC) implementation in Chhattisgarh. Random serum samples (n = 14235) over a period of six years (2010–2016) and stratified random serum samples (n = 269) along with epidemiological parameters by cross-sectional study during 2016–2017 were collected and tested by competitive ELISA for PPR virus antibodies. The overall results from random and stratified sampling indicate that 84% (11989/14235) and 55% (148/269) population represent protective percentage levels of antibodies, respectively. On Chi-square analysis, significant difference was observed in seroconversion rate {between the years 2010–2016 and 2016–2017 (χ2 = 164.88); 2010–2016 (χ2 = 151.95); 2010–2017 (χ2 = 312.74) (P < 0.01)} and across age groups (χ2 = 11.70, p < 0.01) and not between species, breed, sex, and other managemental factors. Further, logistic regression analysis revealed that age groups of animals was significantly (P < 0.05) associated with PPR. The observed seroconversion in the population by stratified random sampling method was lower during 2016–2017 than the world organisation for animal health recommended ∼70%, that indicates annual PPR MVC strategy adopted has not provided desired protection levels. Therefore, vaccination activities need to be continued for three more years by targeting naïve young animals biannually, after that, serosurvey in appropriate sampling method need to be conducted to augur vaccination status and effectiveness of control programme.