Seroprevalence of transfusion transmitted infections among blood donors at a tertiary Care Teaching Hospital of North Gujarat, India

Abstract

Introduction: Transfusion transmitted infections (TTIs) are matter of great concern in today’s world. Meticulous testing of Blood and blood components is must before transfusion so as to avoid risk of getting TTIs. Present study was conducted to find out the seroprevalence of transfusion transmitted infection among the blood donors attending blood bank of rural tertiary care institute. Materials and Method: All blood donors who donated blood at Blood Bank of present institute were screened for transfusion transmitted infections (HIV, HBsAg, HCV, Syphilis) for the year 2010 to 2016 (upto June). Result: Out of total 5434 blood donors, number of male donors were 5275 (97.1%) while 159 (2.9%) were female donors. Voluntary donors were more 76.8% as compared to replacement donors (23.3%). Maximum donors were belonged to 18-30 yrs in all categories. All replacement donors were males. Seroprevalence was more in case of Hepatitis B (1.21%) as compared to other infections. Year wise seroprevalence of transfusion transmitted infections exhibit decreasing trend for all infections excluding Hepatitis B. Significantly high seroprevalence was present in replacement donors. Conclusion: Yearly trend of seroprevalence of HBV was on rise among blood donors as compared to seroprevalence of HIV, HCV and Syphilis. Adult vaccination for hepatitis B should be promoted. Seroprevalence was significantly high among replacement donors which suggest the requirement to motivate voluntary donors for regular blood donation. Keywords: Seroprevalence, HIV, HBsAg, HCV, Syphilis, Blood Donors