Seroprevalence of transfusion transmissible viral infections in blood donors of tertiary health care hospital in Karnataka

Abstract

Backgraound: Blood transfusion and its components are significant in saving millions of lives around the worldwide every year. Few, but serious complications are associated with Blood transfusion such as exposure to transfusion -transmissible infections (TTI), in particular: Human immunodeficiency virus(HIV)Hepatitis B Virus(HBV), Hepatitis C virus (HCV). Therefore, methodical pre transfusion testing of blood units for transfusion transmissible diseases is compulsory as per National Aids Control Organization (NACO) guidelines. Objective: To evaluate the prevalence of transfusion transmissible viral infections among blood donors in our tertiary health care hospital in Bangalore, Karnataka. Materials and Methods: The study comprised of retrospective analysis of blood donor’s records covering from January 2015 to December 2018 (4 years) in the department of Blood bank, Sanjay Gandhi institute of trauma and orthopedics, Bangalore. Results: A total of 8728 blood donors were screened for TTIs between 2015 to 2018. Conclusion: Although there were a smaller number of transfusion transmissible viral infection among blood donors, methodical and comprehensive screening of donor’s blood for HIV, HBV and HCV using standard methods are essential to ensure the safety of blood to the recipients. Keywords: Sero prevalence, Transfusion transmitted infections, Blood donors.