Abstract
Background: Toxoplasma gondii (T.gondii), an obligate intracellular parasite found in many species throughout the world, causes a variety of clinical syndromes in humans and animals. It is also associated with morbidity and mortality in pregnancy. Hence the need to determine the seroprevalence of antibody to toxoplasmosis gondii amongst pregnant women. Methods: A cross-sectional study was carried out using patients attending the ante-natal clinic of Lagos State University Teaching Hospital Ikeja. All consenting newly registered antenatal patients were recruited consecutively into the study within a time frame of six weeks during which a total of 179 pregnant participants were obtained. Participants filled self administered questionnaires. Five milliliters of blood was collected from each participant after obtaining patient's consent. Sera were assayed for antitoxoplasmosis IgG antibody by enzyme linked immunosorbent assay. (ELISA.) Results: A total of 179 pregnant women were studied. An assessment of patients’ status to anti-toxoplasmosis IgG showed 40.8% were positive while 59.2% were negative. Conclusion: It appears that seroprevalence of toxoplasmosis IgG antibody amongst the pregnant women in this study population is high. Therefore, it is valuable to follow up the IgM–antibody status of their off springs which indicates recent exposure. Abstracts for SupplementInternational Journal of Infectious DiseasesVol. 14Preview Full-Text PDF Open Archive
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