Seroprevalence of Torch Infections in Bad Obstetrics History in HIV and Non-HIV Women in Solapur District of Maharashtra India

Abstract

TORCH infections are very important group of infection in day today clinical practice.Some of them are preventable and some are curable to some extent. The study was aimed at evaluating seroprevalence of TORCH infections in HIV negative and HIV positive females with bad obstetric history (BOH). The TORCH test was conducted on 605 HIV negative and 51 HIV positive women. A serological evaluation of TORCH infections was carried out by detecting IgG and IgM antibodies against these infectionsby ELISA method. Number of patients and percentage of HIV negative women were for Toxoplasma IgG 123 (20.66%) IgM 21 (3.47%), Rubella IgG 418 (69.09%) IgM 13 (2.15%), CMV IgG 481(79.50%) IgM 12 (1.98%), HSV-1 IgG 302 (49.92%) IgM 1 (0.17%) and HSV-2 IgG 19 (3.14%) IgM 5(0.83%). Number of patients and percentage of HIV positive women were for Toxoplasma IgG 21 (41.18%) IgM 5 (9.80%), Rubella IgG 50 (98.04%) IgM 4 (7.84%), CMV IgG 50 (98.04 %) IgM 0 (0 %), HSV-1 IgG 44 (86.27 %) IgM 3 (5.88%) and HSV-2 IgG 14 (27.45 %) IgM 3(5.88%). In HIV negative women maximum seroprevalence was observed for CMV followed by Rubella and HSV-1 infection. In HIV positive women seroprevalence for Rubella, CMV and HSV-1 was found maximum and for Toxoplasma gondii and HSV-2 was found minimum. In HIV positive women almost all TORCH infections were found more than in HIV negative women. Studies suggest that early diagnosis and appropriate intervention of these infections may help in proper management of these cases.