Abstract
The present study entitled;” Seroprevalence of Syphilis in Ante natal cases in Central India” was carried out at Govt. Medical College, Nagpur during the period from 2004 to 2008. The study was carried out on 2302 pregnant women attending antenatal clinic of the hospital. In all the cases registered in the clinic, blood was collected for serum VDRL test for detecting reactivity of the sera for syphilis antibodies. The quantitative VDRL test was done by carrying out the test in various titres. The VDRL test was considered as reactive if it showed reactivity in the titres at or more than 1:8 dilutions. The confirmation of diagnosis was by doing Trepanoma Pallidum Haemagglutination (TPHA) test. Amongst 2302 samples studied 61 samples (2.65%) were reactive by qualitative VDRL test. Amongst these 61 cases, the quantitative VDRL test was reactive in 1.26% cases only. Thus the seroprevalence of syphilis antibodies in ANC cases was 1.26%. Detection of syphilis antibodies as early as possible in pregnancy period is important to prevent complications arising out of syphilis.
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