Seroprevalence of syphilis among Sudanese pregnant ladies in Berber city, Sudan

Abstract

Background: Because syphilis is often asymptomatic, it might go unrecognized. Furthermore, infection transfer from mother to unborn child is a concern. Preventing poor pregnancy effects in relation with maternal infection by screening and treating women for syphilis throughout pregnancy. Aiming at exploring anti treponemal antibodies among pregnant women in Berber Teaching Hospital our study was implemented. Methods: A cross-sectional, hospital based study was performed at Berber Teaching Hospital in River Nile State. Encompassed pregnant women who attended Hospital. Following an explanation of the study's goal, 100 serum samples were taken, and data was collected from each respondent using an interview questionnaire, 100 blood samples were obtained to identify syphilis anti bodeis. All specimens were analyzed using the Rapid Plasma Reagin test (RPR), which was confirmed by an enzyme linked immune sorbent assay (ELISA) (fortress diagnostics/UK). Statistical Package for Social Sciences (SPSS version 19) was used to manage informational gathered. Results: ELISA found 9% of syphilis positive patients, whereas RPR identified 10%.Age of respondents ranged between 16 to 43 years, 53 % of study participants categorized at (30 – 36 years) and 62 % at third trimester of gestational. The highest prevalence of syphilis was 4 % reported in age group (23 – 29 years) and 5% at third trimester. Conclusion: The syphilis sero-prevalence among pregnant women in the current research was 9% by ELISA and 10% by RPR. More precise and sensitive procedures, such as PCR, must be used to corroborate the findings