Seroprevalence of Human Papilloma Virus in Aborted Women in Kirkuk City

Jacklen Khoshaba,Salwa Mustafa,Muhannad Alazzawy

doi:10.32441/kjps.02.02.p15

Jacklen Khoshaba, Salwa Mustafa + Show 1 more

Open Access

https://doi.org/10.32441/kjps.02.02.p15

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Abstract

The aimed of the study was to evaluate the Seroprevalence of human papilloma virus (HPV) in aborted women. A cross-sectional study was carried out in Kirkuk city from 10th of March 2017 to 10th of July 2017 The number of aborted women understudy were 65 women who attended for curettage in Kirkuk general hospital. The control group who were matched to the patients studied included 30 normal pregnant women at the full term of pregnancy, women with Toxoplasma gondii , rubella and cytomegalovirus infections were excluded from the study. Five ml of blood was collected by vein puncture from each woman in the study, the obtained sera then organized to determine of HPV 16 E7 protein in patients and control using ELISA technique.The study showed that the highest rate of HPV infection (35.38%) was recorded among women with abortion comparing with the control group, with a highly significant relation. The study showed that 75.38% of women had aborted in the 1st trimester of pregnancy and the lowest rate of abortion 9.24% was in the 3rd trimester. The study showed that the highest rate of HPV infection was found in women with 1st trimester of abortion (38.78%) and the lowest rate was in the 3rd trimester of abortion. The study showed that the highest rate of HPV infection was recorded among aborted women who have suffered from one abortion during their marriage life. It was concluded that there was a significant relation of HPV with abortion spatially in women who were aborted in the first trimester of pregnancy.

Highlights

Recurrent miscarriage, habitual abortion, or recurrent pregnancy loss (RPL) is three or more consecutive pregnancy losses [1]
The study showed that the highest rate of human papilloma virus (HPV) infection (35.38%) was recorded among women with abortion comparing with the control group, with a highly significant relation
The study showed that 75.38% of women had aborted in the 1st trimester of pregnancy and the lowest rate of abortion 9.24% was in the 3rd trimester

Summary

Introduction

Habitual abortion, or recurrent pregnancy loss (RPL) is three or more consecutive pregnancy losses [1]. Recurrent miscarriage (RM) is defined as the occurrence of three or more consecutive losses of pregnancy. According to this definition, it affects about 1% of couples trying to have a baby [2]. Many clinicians define RM as two or more losses; this increases the percentage of RM from 1% to 5% of all couples trying to conceive [3]. Mammalian pregnancy is thought to be a state of immunological tolerance. The mechanisms underlying this phenomenon are still poorly understood, successful mammalian pregnancy depends upon the tolerance of a genetically incompatible fetus by the maternal immune system. When tolerance is not achieved pregnancies fail [1]

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