Seroprevalence of HIV, Hepatitis B and C Virus Infections Among Voluntary and Replacement Blood Donors Attending Al-Sabeen Hospital, Blood Bank, Sana' a City

Abstract

Background: Blood donation saves millions of lives. The blood donor program is the life force of anytransfusion service. Aim: To assess the seroprevalence of transfusion-transmissible infections (HIV,HBV, and HCV) in the voluntary and replacement donors. Methods: The study included 2475 blooddonors both voluntary and replacement blood donors attended at the blood bank, at Al-SabeenHospital, Sana'a, Yemen. The blood samples of all the blood donors were. Few milliliters of eachdonor’s blood were dispensed in a small clean test tube labelled with the name and sample number formandatory screening of the Transfusion. All the blood donors' samples over the period of study werecentrifuged to obtain the serum samples in a small clean test tube labeled with the name and samplenumber were analysed and tested by the immunoassay analyser assay (ELIZA) Cobas e-411 IIndgeneration for anti HIV IgG and IgM antibodies, detection of HBsAg and anti-HCV IgG and IgM.Results: The total Seroprevalence of HIV, HBsAg and HCV was 359 donors in the present study, out ofthem 263 (14.3%) were replacement blood donors and 96 (15.2%) were voluntary blood donors. Thetotal seroprevalence of HIV among blood donors was 42 donors in the present study, out of them 1.8%among replacement blood donors and 1.7% among voluntary blood donors. The total seroprevalenceof HBsAg among blood donors was 286 donors out of them 11.2% among replacement blood donorsand 12.6% of HBsAg among voluntary blood donors. The total seroprevalence of HCV among blooddonors was 31 donors out of them 1.3% were replacement donors and 1.1% were voluntary blooddonors. Conclusion: It has been observed that replacement blood donation is safe as compared tovoluntary as a high prevalence of HIV, HBsAg, and HCV are observed in replacement donors. It isrecommended to following the international standers for the blood collection criteria and screening.