Seroprevalence of HIV-1 and HIV-2 Infections at an ICTC in A Tertiary Care Hospital in Pondicherry

Y Valentina,Johan Pandian

doi:10.22207/jpam.16.1.71

Abstract

Purpose of the study: To estimate the prevalence of HIV 1 and HIV 2 infection in patients attending the tertiary care setup. Routine screening for HIV infection of 10000 samples were carried out between July 2017-June 2018. All patients were given a pre-test counselling and filled up the Consent form provided by NACO. The samples were subjected to the NACO provided Comb Aids RS Advantage kit and all positives were tested using 2 other kits Meriscreen HIV 1-2 and Tridot Test for differentiation. The data thus obtained were charted in Excel and the prevalence were determined. A Post-test counselling was given for all patients and the results were disclosed following the protocol provided by NACO. Of the 10000 samples, 82 (0.82%) samples were reactive for HIV. In the 82 reactive samples, 78 (95.12%) samples were reactive for HIV- 1 antibodies and 4 (4.8%) samples were reactive for HIV-2 antibodies. Among the 82 reactive clients, 53 clients were male and 29 clients were female.

Highlights

In 2015, the HIV disease burden in India was estimated by UNAIDS as 15.8 million.[1]
A Post-test counselling was given for all patients and the results were disclosed following the protocol provided by NACO
In the 82 reactive samples, 78 (95.12%) samples were reactive for HIV- 1 antibodies and 4 (4.8%) samples were reactive for HIV-2 antibodies

Summary

Introduction

In 2015, the HIV disease burden in India was estimated by UNAIDS as 15.8 million.[1]. The mode of infection of HIV1 & HIV-2 appears to be similar. Transmission of HIV-2 is mainly by sexual contact followed by transfusion of infected blood. Though HIV-2 was limited to parts of West Africa, it's currently seen in different continents, due to the history of frequent sexual contact of the foreigners with commercial sex workers (CSW).[4] They act as a means for transmitting HIV-2 from higher prevalent areas, such as parts of West Africa, to lower prevalent countries, like India. Seroprevalence of human immunodefciency virus type 2 infection from a tertiary care hospital in Pune, Maharashtra: A 2 year study. Recent trend of HIV infection at ICTC in a tertiary care hospital in North. MedPub. 2015;7(3:3):[1,2,3,4]

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Results

Conclusion