Seroprevalence of HBV Infection in a Tertiary Care Hospital in Bangladesh

Abstract

An estimated 1 million people die each year from HBV infection. This investigation aimed to determine the frequency, distribution, and risk factors for HBV infection in a healthy Bangladeshi community. A cross-sectional study among the general population was conducted in Dhaka Medical College Hospital. A series of 100 patients with the chronic liver disease between 18 to 49 years. Diagnosed based on clinical and biochemical parameters were collected. All medicine units of Dhaka Medical College Hospital have been analyzed regarding the seroprevalence of HBsAg and its correlation with the demographic pattern. Among 100 cases of liver disease, the number of CLD patients was 85, of which 56 (65.88%) were HBsAg positive 29 (34.11%) were HBsAg negative. The number of patients with acute viral hepatitis was 15, of which 4(26.66%) were HBsAg positive, 11(73.33%) were HBsAg negative, and the overall seroprevalence was 60%. The age incidence was more below 40 years (83%) less above the age of 40(17%). Males had higher seropositivity (70.31%) than females (41.66%). People of all ages are susceptible, particularly the farmers (21.66%) and manual laborers (13.33%). Most of the patients belong to the poor (62.79%) and middle class (62.22%). Urban people were more (60.93%) susceptible than rural people (58.33%). Married persons were more (70.27%) prone than unmarried (30.76%). Seroprevalence of HBsAg was more in those people who had a history of blood and blood product transfusion (84.61%). Illiterate persons were more (75%) susceptible than literate (59.37%). Seroprevalence of HBsAg was more in those who had a history of instrumental tooth extraction (68.42%) than those who had not (58.02%). People who cut their beards and mustache in the barbershop were more susceptible (73.91%) than those who got it by themselves (68.29%). Among female persons, those who underwent instrumental delivery were more susceptible than those who delivered their baby by normal vaginal delivery.