Seroprevalence of cytomegalovirus and toxoplasmosis in cases of miscarriages women in Al-Diwaniyah province

Abstract

A total of 125sera were collected from miscarriages women and healthy as control group. Latex agglutination test (LAT) and Enzyme linked Immunosorbent Assay (ELISA) were used to assess the presence of specific antibodies against T.gondii and CMV. 65(43&22) were positive for anti-Toxoplasma antibody. While 74 sera, (54 & 20) were positive for anti-CMV IgG and IgM antibodies respectively.and healthy as control group. Latex agglutination test (LAT) and Enzyme linked Immunosorbent Assay (ELISA) were used to assess the presence of specific antibodies against T.gondii and CMV. 65(43&22) were positive for anti-Toxoplasma antibody. While 74 sera, (54 & 20) were positive for anti-CMV IgG and IgM antibodies respectively Whereas all control group 25 have been found to be negative for both T. gondii and CMV. The occurrence of two pathogens in relation to the residence, age and occupation has been studied. This study was conducted to detect the role of T. gondii and CMV in cases of miscarriage and detect the possible association between the two infections at the Children Maternity Hospital and private laboratories in Al-Diwaniyah Province during the period from November 2009 to march 2010. The study has found that the highest prevalence of Toxoplasmosis recorded for women in the second trimester of pregnancy, whereas in the first trimester for CMV infection and in women with multiple abortions more than with single abortion for both pathogens.