Seroprevalence of COVID-19 IgM and IgG antibodies among asymptomatic individuals in Khartoum State-2020

Abstract

Background: Seroprevalence detection of antibodies to severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) in apparent healthy individuals will be critical for the public health response to the coronavirus disease 2019 pandemic. The aim of this study was to investigate the prevalence of IgM and IgG to covid-19 in Khartoum State. Patients and methods: A cross-sectional retrospective laboratory-based investigation was conducted in Khartoum State 2020. Apparent healthy individuals without obvious respiratory conditions, and in order to obtain a travel license were exempted; however individuals who fulfilled the participation requirements were allowed to participate. After informed consent and fitting eligibility qualifications, a blood sample was taken from each respondent and used to identify SARS-CoV-2 IgM and IgG antibody tests in COVID-19 suspected informants using a snibe system model Maglumi 800. The Statistical Package for Social Sciences (SPSS) version 23 was used for statistical analysis in form of frequencies. Results: In the state of Khartoum, a total of 1000 samples were collected from participants to determine seroprevalence of covid-19; of these, 224 were reactive and 776 were nonreactive. There were 158 reactive IgG and 66 reactive IgM within that reactive covid-19 patient. Conclusion: There was a high prevalence of SARS-CoV-2 antibodies among asymptomatic respondents in Khartoum state.